Micronucleus Test Using Peripheral Red Blood Cells of Amphibian Larvae for Detection of Genotoxic Agents in Freshwater Pollution

  • A. Jaylet
  • L. Gauthier
  • C. Zoll
Part of the Environmental Science Research book series (ESRH, volume 38)


Increased environmental pollution can be attributed to a variety of factors resulting from new industrial and agricultural technologies together with changes in our way of life. Moreover, the nature of the pollution itself has become more diverse. Whatever the origin of the pollution it tends to find its way into the aquatic environment. Genotoxic pollutants affect the aquatic ecosystem, and their presence in the water can also have repercussions on non-aquatic species via food chains or simply from drinking the polluted water. Man is not exempt from this risk; much drinking water is derived from surface water that is more or less polluted. Before distribution to the consumer, this water is thus subjected to a number of treatments. Ironically, if the water is rich in organic matter some disinfectant treatments may in fact lead to the formation of genotoxic compounds that were not present in the initial water source. One should therefore be aware of the hidden risks stemming from potential genotoxins in the aquatic environment. Moreover, a considerable time may elapse between the action of the mutagenic agent and the outward signs of its effects. The relationship between cause and effect may thus become obscured.


Methyl Mercury Mutagenic Agent Micronucleus Test Genotoxic Agent Ethyl Methane 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • A. Jaylet
    • 1
  • L. Gauthier
    • 1
  • C. Zoll
    • 1
  1. 1.Centre de Biologie du DeveloppementUA No. 675 (CNRS) Universite Paul SabatierToulouse CedexFrance

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