Abstract
Drosophila melanogaster was the principal organism used for the development of diploid transmission genetics at the beginning of the century and more recently has been the subject of pivotal studies on eucaryote gene regulation, development and behavior. D. melanogaster is potentially valuable for in situ biomonitoring because it is convenient to test different life stages, it can be used for a multi-faceted analysis of environmental genotoxins and a rapidly expanding base of information on its molecular genetics facilitates the development of new methods for bioassays.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abraham, S.K., Goswami, V. and Kesavan, P.C., 1979, Mutagenicity of inhaled diethyl sulfate vapour in Drosophila melanogaster and its implications for the utility of the system for screening air pollutants, Mut. Res. 66: 195–198.
Abrahamson, S. and Lewis, E.B., 1971, The detection of mutations in Drosophila melanogaster, In: “Chemical Mutagens, Vol. 2,” A. Hollaender (ed.), Plenum Press, N.Y.
Borkovec, A.B., 1973, Insect chemosterilants as mutagens, In: “Chemical Mutagens, Vol. 3,” A. Hollaender (ed.), Plenum Press, N.Y.
Green, M.M., Todo, T., Ryo, N. and Fujikawa, K., 1986, Genetic-molecular basis for a simple Drosophila melanogaster somatic system that detects environmental mutagens, P.N.A.S. 83: 6667–6671.
Harshman, L.G., Ottea, J.A. and Hammock, B.D., Environment-dependent expression of detoxication enzyme activity in a Drosophila melanogaster selection experiment, Evolution submitted manuscript.
Harshman, L.G., Green, M.M., MacKay, W., Bewley, G. and Edlin, G., Relative survival of catalase deficient genotypes on irradiated Drosophila food, Drosophila Information Service, submitted manuscript.
Hayes, W.J., 1968, Toxicological aspects of chemosterilants, In: “Principles of Insect Chemosterilization,” G.C. Labrecque and C.N. Smith (eds.), Appleton-Century-Crafts, New York.
Jones, P.B.C., Galeazzi, D.R., Fisher, J.M. and Whitlock, J.P., 1985, Control of cytochrome P1–450 gene expression by dioxin, Science 227:1499–1502.
Pereira, M.A., 1983, International symposium on tumor production, Envir. Health Perspect. 50:3–370.
Roberts, D.B., 1986, Basic Drosophila care and techniques, In: “Drosophila, A Practical Approach,” D.B. Roberts (ed.), IRL Press, Washington D.C.
Sankaranarayanan, K., 1979, The role of non-disjunction in aneuploidy in man: An overview, Mut. Res. 61: 1–28.
Shakarnis, V.F., 1969, Induction of X chromosome non-disjunction and recessive sex-linked mutations in females of Drosophila melanogaster by 1,2-dichloroethane, Sov. Genet 5: 1666–1671.
Valencia, R., Abrahamson, S., Lee, W.R., Von Halle, E.S., Woodruff, R.C., Wurgler, F.E. and Simmering, S., 1984, Chromosome mutation tests for mutagenesis in Drosophila melanogaster, Mut. Res. 134: 61–88.
Verburgt, F.G. and Vogel, E., 1977, Vinyl chloride mutagenesis in Drosophila melanogaster, Mut. Res. 48: 327–336.
Vogel, E. and Sobels, F.N., 1976, The function of Drosophila in genetic toxicology testing, In:“Chemical Mutagens, Vol. 4,” A. Hollaender (ed.), Plenum Press, N.Y.
Zimmering, S. and Kammermeyer, K.L., 1983, Comparison of excision repair-deficient mei-9 and mus 201 females in the test for paternal sex chromosome loss in Drosophila with procarbazine and diethylnitrosamine (DEN), Environ. Mutagen. 5:235–237.
Zimmering, S., Mason, J.M. and Osgood, C., 1986, Current status of aneuploidy testing in Drosophila, Mut. Res. 167: 71–87.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Harshman, L.G., Hammock, B.D. (1990). The Use of Drosophila Melanogaster for In Situ Biomonitoring. In: Sandhu, S.S., Lower, W.R., de Serres, F.J., Suk, W.A., Tice, R.R. (eds) In Situ Evaluation of Biological Hazards of Environmental Pollutants. Environmental Science Research, vol 38. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5808-4_18
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5808-4_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5810-7
Online ISBN: 978-1-4684-5808-4
eBook Packages: Springer Book Archive