A Versatile, New Accelerator Design for Boron Neutron Capture Therapy: Accelerator Design and Neutron Energy Considerations

  • R. E. Shefer
  • R. E. Klinkowstein
  • J. C. Yanch
  • G. L. Brownell
Part of the Basic Life Sciences book series (BLSC, volume 54)


The development of a new, compact high-current proton accelerator by Science Research Laboratory (SRL) capable of producing large quantities of neutrons fits closely with the recent interest in the use of epithermal neutrons for Boron Neutron Capture Therapy (BNCT). Three important facets of this development are currently being investigated. These include 1) the production of neutrons by the 7Li(p,n) reaction using a novel tandem cascade electrostatic accelerator, 2) the optimal neutron energy (or range of energies) for treatment of tumors at different depths in tissue, and 3) the extent of moderation and filtering required to reduce the energy of the accelerator neutrons to the energies deemed optimal in (2) above. The overall goal is to develop a versatile epithermalneutron source which will be, initially, a valuable research tool in the development of BNCT, and ultimately, an essential component of a hospital-based patient irradiation facility.


Neutron Energy Neutron Beam Neutron Yield Boron Neutron Capture Therapy Epithermal Neutron 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • R. E. Shefer
    • 1
  • R. E. Klinkowstein
    • 1
  • J. C. Yanch
    • 2
  • G. L. Brownell
    • 2
  1. 1.Science Research LaboratorySomervilleUSA
  2. 2.Department of Nuclear EngineeringMassachusetts Institute of TechnologyCambridgeUSA

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