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Kindling as a Model of Long-Lasting Plasticity: New Perspectives in the Search for Molecular Mechanisms

  • Gildas Le Gal La Salle
Part of the Advances in Behavioral Biology book series (ABBI, volume 37)

Abstract

Twenty years after its discovery, kindling continues to give rise to an increasing interest as attested by this fourth symposium and the impressive number of papers dealing with this subject in the literature. But, as kindling studies advance, the objectives tend to differ. Although kindling was initially recognized as a suitable model for studying plasticity, it served primarily in epilepsy research. A considerable amount of works were devoted to the analysis of antiepileptic drugs and the study of the neurobiological basis of epileptogenesis. Now, the overall tendency is to reconcile both aspects in again considering kindling as a model of plasticity. A paper on this subject is presented in the book Kindling 3 (27).

Keywords

Nerve Growth Factor Mossy Fiber Synaptic Remodel Hippocampal Mossy Fiber Sprouted Mossy Fiber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Gildas Le Gal La Salle
    • 1
  1. 1.Laboratoire de Physiologie Nerveuse, Département de Neuropharmacologie MoléculaireCentre National de la Recherche ScientifiqueGif-sur-YvetteFrance

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