Effects of a Neurotrophic Factor (FGF) on Development, Regeneration and Synaptic Plasticity of Central Neurons

  • W. Seifert
  • F. Förster
  • B. Flott
  • H. Terlau
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 268)


Fibroblast growth factor (FGF) was originally isolated from bovine brain and pituitary and described as a mitogenic factor for fibroblasts and other cell types of mesodermal origin (1,2). In recent years two astroglial growth factors (AGF1 and AGF2) were purified from bovine brain and demonstrated to be identical with basic and acidic fibroblast growth factor (3). In the following the term FGF is used only for the basic factor (bFGF) of molecular weight 16.000.


Fibroblast Growth Factor Neurotrophic Factor Synaptic Plasticity Long Term Potentiation Hippocampal Slice 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • W. Seifert
    • 1
  • F. Förster
    • 1
  • B. Flott
    • 1
  • H. Terlau
    • 1
  1. 1.Dept.of NeurobiologyMax-Planck-Institut f. biophys. ChemieGöttingenW-Germany

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