Different Mechanisms and Multiple Stages of LTP
On the basis of our own experimental data and results from other laboratories then available, we developed in 1972 a working hypothesis on neuronal mechanisms of memory. We suggested that the assumed stages of short-term, intermediate, and long-term memory, their different time course of origin and decay, their biochemical correlates as well as their sensitivity to interventions reflect the properties of the corresponding cellular mechanisms of a synaptic, synaptosomal and nuclear regulation of memory formation (Matthies, 1972).
KeywordsDentate Gyrus Perforant Path Impulse Train Train Interval Early Maintenance
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