The Role of Taurine and Glutamate during Early Postnatal Cerebellar Development of Normal and Weaver Mutant Mice

  • E. Trenkner
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 268)


It is generally accepted that the stimulation of neurotransmitter receptors can lead to the differentiation of neuronal cells1,2. That astroglial cells might play an active role in this developmental process was suggested, but its molecular mechanism still remains elusive. This study analyzes the interaction between cerebellar granule cell neurons (GC) and astroglial cells based on an amino-acid-transmitter mediated regulation mechanism.


Granule Cell Excitatory Amino Acid Astroglial Cell Mouse Cerebellum Taurine Concentration 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • E. Trenkner
    • 1
  1. 1.Department of PathologyColumbia University, Physicians & SurgeonsNew YorkUSA

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