Radiosensitizing Effect of Hyperthermia in Radioresistant Tumours

Comparative Studies in Vivo and in Vitro
  • W. Burkhard
  • M. Notter
  • N. Schwegler
  • H. Fritz-Niggli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 267)


The prospect of a successful introduction of hyperthermia in the field of radiooncology increased during the last few years as a result of the technical realization of selective and controlled heat applications in well defined and also deep seated target volumes. This lead to extensive radiobiological studies on this subject (10). Possible side effects as the development of “thermotolerance”, an adaptive reaction of the tissue ( 2 , 4 , 6 , 8 , 9 ) , as well as cytotoxicity of heat treatments were discussed (1,5).


Adaptive Reaction Radiotherapy Departement RADIORESISTANT Tumour Clonal Assay Radiosensitizing Agent 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • W. Burkhard
    • 1
    • 2
  • M. Notter
    • 2
  • N. Schwegler
    • 2
  • H. Fritz-Niggli
    • 1
    • 2
  1. 1.Radiobiological Inst.Univ. of ZurichZurichSwitzerland
  2. 2.StrahlentherapieKantonsspital AarauAarauSwitzerland

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