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Thermoradiotherapy of Deep Seated Tumours of the Pelvis with the APA and Sigma Applicator

  • H. J. Feldmann
  • M. Molls
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 267)

Abstract

Clinical and experimental studies have shown the potential benefit of hyperthermia combined with radiotherapy (Overgaard 1989). Concerning superficial tumours clinical studies confirm that the combined treatment with both modalities increases the rate of complete and partial responses. However, when compared with superficial tumours heating of deep seated malignancies is more difficult. At present the most reliable method of external deep hyperthermia is the application of electromagnetic-wave hyperthermia which can be performed with the commercially available BSD 1000 (APA) and 2000 (SIGMA) devices (BSD Medical Corporation, Salt Lake City, USA). This procedure deposits power throughout a large volume of tissue including the tumour and surrounding normal tissues (Howard et al., 1986, Kappet al., 1988; Molls et al., 1989; Petrovich et al., 1989; Pilepich et al., 1988). The clinical results of regional hyperthermia are presented with respect to the following four topics:
  1. 1.

    Tumour temperatures and thermal dose

     
  2. 2.

    Normal tissue temperatures

     
  3. 3.

    Toxicity

     
  4. 4.

    Response

     

Keywords

Thermal Dose High Maximum Temperature Tumour Temperature Regional Hyperthermia Normal Muscle Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • H. J. Feldmann
    • 1
  • M. Molls
    • 1
  1. 1.Department of RadiotherapyWest German Tumour CentreEssenGermany

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