Thermoradiotherapy of Deep Seated Tumours of the Pelvis with the APA and Sigma Applicator
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 267)
Clinical and experimental studies have shown the potential benefit of hyperthermia combined with radiotherapy (Overgaard 1989). Concerning superficial tumours clinical studies confirm that the combined treatment with both modalities increases the rate of complete and partial responses. However, when compared with superficial tumours heating of deep seated malignancies is more difficult. At present the most reliable method of external deep hyperthermia is the application of electromagnetic-wave hyperthermia which can be performed with the commercially available BSD 1000 (APA) and 2000 (SIGMA) devices (BSD Medical Corporation, Salt Lake City, USA). This procedure deposits power throughout a large volume of tissue including the tumour and surrounding normal tissues (Howard et al., 1986, Kappet al., 1988; Molls et al., 1989; Petrovich et al., 1989; Pilepich et al., 1988). The clinical results of regional hyperthermia are presented with respect to the following four topics:
Tumour temperatures and thermal dose
Normal tissue temperatures
KeywordsThermal Dose High Maximum Temperature Tumour Temperature Regional Hyperthermia Normal Muscle Tissue
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- 3.Kapp, D. S., Fessenden, P., Samulski, T. V., Bagshaw, M. A., Cox, R. S., Lee, E. R., Lohrbach, A. W., Meyer, J. L., Prionas, S. D.,1988, Stanford University Institutional Report. Phase I evaluation of equipment for hyperthermic treatment of cancer. Int. J. Hyperthermia 4: 75.PubMedCrossRefGoogle Scholar
- 4.Molls, M., Feldmann, H. J., Baumhoer, W., Sack, H., 1989, Radiotherapy and regional hyperthermia: Thermal profiles and treatment results, in: “Proceedings of the 5th International Symposium on Hyperthermic Oncology”, Kyoto, Japan, in press.Google Scholar
- 6.Petrovich, Z., Langholz, B., Gibbs, F. A., Sapozink, M. D., Kapp, D. S., Stewart, R. J., Emami, B., Oleson, J., Senzer, N., Slater, J., Astrahan, M., 1989, Regional hyperthermia for advanced tumours: A clinical study of 353 patients. Int. J. Radiat. Oncol. Biol. Phys. 16: 601.PubMedCrossRefGoogle Scholar
- 8.Samulski, T. V., Kapp, D. S., Fessenden, P., Lohrbach, A. W.,1987, Heating deep seated eccentrically located tumors with an annular phased array system: A comparative clinical study using two annual array configurations. Int. J. Radiat. Oncol. Biol. Phys. 13: 83.Google Scholar
© Plenum Press, New York 1990