The Basis for Hyperthermia Becoming the Fourth Cancer Treatment Modality in the 1990’s

  • John R. McLaren
  • Paolo Pontiggia
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 267)


At and following the International Symposium of Hyperthermia, sponsored by the American College of Radiology at Baltimore in 1978, there was much optimism based upon biological and physical data that heat as the fourth modality for the treatment of cancer would evolve. In spite of firm foundations for the clinical use of heat and in spite of extensive engineering toward the application of space age technology to adequately heat cancer patients and with financing from several sources many questions remain unanswered. Many investigators previously guardedly optimistic have gradually become disappointed and somewhat pessimistic, and financing has tightened over the past decade. Much of the present clinical work, due to equipment limitations, is directed largely to more superficial cancers most available to surgery and radiation for definitive treatment. Many are asking “Wither hyperthermia in the 1990’s?”


Surrounding Normal Tissue Hyperthermia Treatment Fourth Modality Nutritional Deprivation Regional Hyperthermia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • John R. McLaren
    • 1
  • Paolo Pontiggia
    • 2
  1. 1.Emory University School of MedicineAtlantaUSA
  2. 2.Department of Hematology OncologyClinica Citta di PaviaPaviaItaly

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