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Overview of Whole Body Hyperthermia Experience at American International Hospital

  • Ranulfo Sanchez
  • Robert D. Levin
  • Young Doo Kim
  • Alfonso Mellijor
  • Mary Ann Doyle
  • William Simonich
  • R. Michael Williams
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 267)

Abstract

Whole body hyperthermia (WBH) with general anaesthesia, utilizing the heated water blanket technique of Barlogie et all and of Larkin2, have been utilized in 427 patients at American International Hospital (AIH) from 1978 thru 1987. After an early developmental phase, we now treat to achieve a core body temperatures of 42.2°C for two hours with a rapid cool-down phase. Most patients received WBH once each month with chemotherapy beginning 18 hours after completion of WBH.This was done in an attempt to utilize WBH in its optimum conditions, and to utilize a wide range of chemotherapy drugs, given in combinations and doses felt optimum for patient care in the absence of WBH. These studies were primarily intended to confirm the safety of both forms of therapy given sequentially.

Keywords

Prior Chemotherapy Regimen Whole Body Hyperthermia Body Hyperthermia Colon Carcinoma Patient Early Developmental Phase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    B. Barlogie, P. M. Corry, E. Yip, et al, Total Body Hyperthermia with and without Chemotherapy for Advanced Human Neoplasms, Cancer Res. 39: 1481 (1979).PubMedGoogle Scholar
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    J. M. Larkin, W. S. Edwards, D. E. Smith, and P. J. Clark. ystemic Thermotherapy: Description of a Method and Physiologic Tolerance in Clinical Subjects, Cancer 40: 3155 (1977).PubMedCrossRefGoogle Scholar
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    R. D. Levin, R. Sanchez, Y. D. Kim, A Mellijor, M. A. Doyle, W. Simonich, and R. M. Williams. Studies of Whole Body Hyperthermia (WBH) with Chemotherapy (CH) in Metastatic Breast Cancer, Submitted.Google Scholar
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    R. D. Levin, R. Sanchez, Y. D. Kim, A. Mellijor, M. A. Doyle, W. Simonich, and R. M. Williams. Whole Body Hyperthermia Experience in Breast Cancer at American International Hospital. This volume.Google Scholar
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Ranulfo Sanchez
    • 1
  • Robert D. Levin
    • 1
  • Young Doo Kim
    • 1
  • Alfonso Mellijor
    • 1
  • Mary Ann Doyle
    • 1
  • William Simonich
    • 1
  • R. Michael Williams
    • 1
  1. 1.American International HospitalZionUSA

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