S-100 Proteins: Relationships with Membranes and the Cytoskeleton

  • Rosario Donato
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 269)


Proteins of the S-100 family, S-100a0 (αα), (αß), and S-100b (ßß) belong to the superfamily of Ca2+-binding proteins of the EF-hand type (for review see Donato, 1986). S-100 proteins are widely distributed in animal tissues, yet they are not ubiquitous. In the brain, ~ 85% of S-100 is soluble in the cytoplasm and 15% of it is associated with membranes.


Electron Spin Resonance Bovine Brain Brain Membrane Culture Schwann Cell Skeletal Muscle Membrane 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Rosario Donato
    • 1
  1. 1.Section of AnatomyDepartment of Exper. Med. and Biochem. SciencesPerugia Succ. 3Italy

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