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Ca2+-Binding Proteins as Components of the Cytoskeleton

  • Michael Schleicher
  • Ludwig Eichinger
  • Walter Witke
  • Angelika A. Noegel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 269)

Abstract

One of the major filamentous systems of non-muscle cells is based on actin, a highly conserved protein of 42kD. The polymerization equilibrium between globular (G-) and filamentous (F-) actin determines the viscosity of the cytoplasm and is regulated by cytoplasmic salt conditions and by actin-binding proteins (for review see Stossel et al., 1985, Pollard and Cooper, 1986). Several of these actin-binding proteins are activated or inhibited by micromolar Ca2+-concentrations either through direct binding to Ca2+ or indirectly through modulators such as calmodulin.

Keywords

Dictyostelium Discoideum Chicken Brain 42bp Oligonucleotide Chicken Fibroblast Brain Spectrin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Michael Schleicher
    • 1
  • Ludwig Eichinger
    • 1
  • Walter Witke
    • 1
  • Angelika A. Noegel
    • 1
  1. 1.Max-Planck-Institute for BiochemistryMartinsriedGermany

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