Functional Aspects of the cGMP-Activated Channel from Bovine Rod Outer Segments

  • W. Hanke
  • R. Simmoteit
Part of the Series of the Centro de Estudios Científicos de Santiago book series (SCEC)


The cGMP-activated channel of the plasma membrane of bovine rod outer segments is responsible for the change of the electrical potential of this membrane,1) which occurs after the absorption of light by rhodopsin in the disk membrane. The plasma membrane hyperpolarizes due to the closing of such channels, when the cGMP concentration drops as a consequence of the activation of an enzyme cascade.


Native Membrane Planar Lipid Bilayer Hill Plot cGMP Concentration Crude Membrane Preparation 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • W. Hanke
    • 1
  • R. Simmoteit
    • 1
  1. 1.FB Biologie, BiophysikUniversität OsnabrückOsnabrückFederal Republic of Germany

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