What We Know and What We Would Like to Know About the Role of Inositol 1,4,5-Trisphosphate in Skeletal Muscle

  • Pompeo Volpe
  • Francesco Di Virgilio
  • Tullio Pozzan
Part of the Series of the Centro de Estudios Científicos de Santiago book series (SCEC)


In skeletal muscle, the depolarization of the transverse tubule (TT) membrane system evokes Ca2+ release from the terminal cisternae (TC) of the sarcoplasmic reticulum (SR), a specialized endomembrane network. The coupling between excitation and contraction occurs at the triad where TT and TC are associated junctionally via bridging structures, also referred to as “feet.”


Skeletal Muscle Sarcoplasmic Reticulum Skeletal Muscle Fiber Inositol Trisphosphate Rabbit Skeletal Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Pompeo Volpe
    • 1
  • Francesco Di Virgilio
    • 2
  • Tullio Pozzan
    • 2
  1. 1.Department of Physiology and BiophysicsThe University of Texas Medical BranchGalvestonUSA
  2. 2.Centro di Studio per la Fisiologia dei Mitocondri del CNRIstituto di Patologia Generale dell’ Université di PadovaPaduaItaly

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