Role of Slow Inward Calcium Current in Excitation-Contraction Coupling

  • Vincent Jacquemond
  • Oger Rougier
Part of the Series of the Centro de Estudios Científicos de Santiago book series (SCEC)


The role of external calcium in the process of excitation-contraction coupling of skeletal muscle fibers had been investigated extensively. Removal of external calcium has been shown to not prevent the contractile activation, but it does have distinct effects on contracture amplitude and duration and on the voltage-dependence of contractile inactivation.(1–5) Furthermore, it has been demonstrated recently that the magnitude and time course of myoplasmic calcium transients elicited by membrane depolarization depend strongly on extracellular calcium.(6)


Contractile Response Slow Phase Calcium Current Skeletal Muscle Fiber Voltage Sensor 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Vincent Jacquemond
    • 1
  • Oger Rougier
    • 1
  1. 1.Laboratoire de Physiologie des Elements ExcitablesUniversité Claude BernardVilleurbanne CedexFrance

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