Stimulus-Response Coupling in Mammalian Ciliated Cells: The Role of Ca2+ in Prostaglandin Stimulation

  • Manuel Villalon
  • Pedro Verdugo
Part of the Series of the Centro de Estudios Científicos de Santiago book series (SCEC)


Calcium has been thought to play an important role in the control of ciliary movement in a broad variety of ciliated cells. In mammalian ciliated cells Ca2 + depletion can cause reversible ciliary arrest. Also, ciliostimulation produced by prostaglandins in ciliated cells of the oviduct is thought to be coupled by release of intracellular Ca2+. However, direct measurements of fluctuations of intracellular [Ca2+] associated with stimulation of ciliary activity have not been reported.


Ciliated Cell Ciliary Activity Ciliary Movement Paramecium Caudatum Chemical Message 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Manuel Villalon
    • 1
  • Pedro Verdugo
    • 1
  1. 1.Center for BioengineeringUniversity of WashingtonSeattleUSA

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