Synexin-Driven Membrane Fusion: Molecular Basis for Exocytosis

  • Eduardo Rojas
  • A. Lee Burns
  • Harvey B. Pollard
Part of the Series of the Centro de Estudios Científicos de Santiago book series (SCEC)


Secretion by exocytosis involves fusion of a secretory vesicle membrane with the plasma membrane of the secreting cell. In many endocrine cells, including chromaffin cells and pancreatic β-cells, such simple exocytosis is followed by contact and fusion of more deeply situated secretory vesicles with the initially fused secretory vesicle membranes. The latter process is called compound exocytosis, and presumably allows for additional secretion without moving secretory granules long distances through the cytoskeleton to reach the plasma membrane.


Chromaffin Cell Phosphatidic Acid Membrane Fusion Current Transient Adrenal Chromaffin Cell 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Eduardo Rojas
    • 1
  • A. Lee Burns
    • 1
  • Harvey B. Pollard
    • 1
  1. 1.Laboratory of Cell Biology and Genetics, National Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthBethesdaUSA

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