Free Radicals and Trials of Antioxidant Therapy in Muscle Diseases
It has been recognised for a number of years that the severest forms of the degenerative muscular dystrophies share many of the characteristics of vitamin E or selenium deficiency myopathy of animals and indeed the animal disorders have been incorrectly termed ’nutritional muscular dystrophies’ [Bradley and Fell, 1980]. The recognition that the major functions of vitamin E and selenium within the body are likely to be as antioxidants acting to inhibit the toxic effects of free radicals has prompted investigations of the possible role of free radicals in some of the human disorders, particularly myotonic and Duchenne muscular dystrophies.
KeywordsMuscular Dystrophy Duchenne Dystrophy Duchenne Muscular Dystrophy Myotonic Dystrophy Muscle Disease
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