Antioxidant Activity in Fetal and Neonatal Lung

  • Mary McElroy
  • Tony Postle
  • Frank Kelly
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 264)


Preterm infants, especially those born 8–15 weeks prematurely, have a high risk of developing respiratory distress syndrome [RDS]. RDS is caused by a relative lack of pulmonary surfactant and is characterized by areas of lung collapse and the deposition of protein containing hyaline membranes within the alveolus (Battenburg, 1982). RDS is treated by positive pressure ventilation together with supplemental oxygen; the success of this therapy can be seen by the greater than 50% survival rate of infants delivered as early as 26 weeks of gestation in many centres.


Antioxidant Enzyme Activity Patent Ductus Arteriosus Positive Pressure Ventilation Pulmonary Surfactant Neonatal Lung 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Mary McElroy
    • 1
  • Tony Postle
    • 1
  • Frank Kelly
    • 1
  1. 1.Departments of Human Nutrition and Child HealthUniversity of SouthamptonSouthamptonUK

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