Antioxidant Activity in Fetal and Neonatal Lung
Preterm infants, especially those born 8–15 weeks prematurely, have a high risk of developing respiratory distress syndrome [RDS]. RDS is caused by a relative lack of pulmonary surfactant and is characterized by areas of lung collapse and the deposition of protein containing hyaline membranes within the alveolus (Battenburg, 1982). RDS is treated by positive pressure ventilation together with supplemental oxygen; the success of this therapy can be seen by the greater than 50% survival rate of infants delivered as early as 26 weeks of gestation in many centres.
KeywordsAntioxidant Enzyme Activity Patent Ductus Arteriosus Positive Pressure Ventilation Pulmonary Surfactant Neonatal Lung
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