Reactive Oxygen Species Released by Human Blood Neutrophils Piroxicam-Treated Healthy Subjects
The polymorphonuclear neutrophils (PMNs) are known to be the major infiltrating phagocytes in the synovia of inflammatory joints in patients with rheumatoid arthritis. A continued extravasation of peripheral blood PMNs occurs to maintain the high local concentration of these cells (1). Therefore, it seems to be important to study the ability of these blood leucocytes to respond to various stimuli for a better understanding of the effects of anti-inflammatory drugs.
KeywordsPhorbol Myristate Acetate Arachidonic Acid Metabolism High Local Concentration Arachidonic Acid Metabolite Lipoxygenase Pathway
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