Mechanism Whereby Different Anti-Oxidants and Lipoxigenase Pathway Inhibitors Suppress IL2 Synthesis
It has been reported by several authors (1) and ourselves (2,3,4) that oxidatlve processes have been implicated in T cell responses. It wes found that several types of anti-oxidants suppressed T cell response, but that LO inhibitors display specific characteristics when compared to the other antioxidants.
KeywordsAccessory Cell Splenocyte Proliferation Murine Thymocyte Membrane Phospho Anti Port
Unable to display preview. Download preview PDF.
- 1.G. Chaudri, I.A.Clark, N.H.Hunt, W.B.Cowden, R.Ceredìg Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. J.lmmunol. 137:2646 (1986).Google Scholar