Mechanism Whereby Different Anti-Oxidants and Lipoxigenase Pathway Inhibitors Suppress IL2 Synthesis

  • Jacques Dornand
  • Mariette Gerber
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 264)


It has been reported by several authors (1) and ourselves (2,3,4) that oxidatlve processes have been implicated in T cell responses. It wes found that several types of anti-oxidants suppressed T cell response, but that LO inhibitors display specific characteristics when compared to the other antioxidants.


Accessory Cell Splenocyte Proliferation Murine Thymocyte Membrane Phospho Anti Port 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Jacques Dornand
    • 1
  • Mariette Gerber
    • 2
  1. 1.Laboratoire de Biochimie des Membranes, Ecole de ChimieCNRSMontpellierFrance
  2. 2.Centre Paul LamarqueINSERMMontpellierFrance

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