Antioxidative Action of Zinc-Carnosine Compound Z-103
The objective of the present study was to examine the anti-free radical action of Z-103 in vitro. Z-103 is a novel synthetic compound of zinc and carnosine (β-alanyl-L-histidine) which has strong anti-ulcer action in many types of animal models.1Free radicals have come to considered to be playing a role in the pathogenesis of gastric mucosal injuries2,3. The antifree radical action of Z-103 were expected because zinc and carnosine have antioxidative properties4,5. To know its anti-free radical action in vitro will be significant to understand its mechanism of action as anti-ulcer drug.
KeywordsLipid Peroxidation Electron Spin Resonance Xanthine Oxidase Ferrous Iron Electron Spin Resonance Signal
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