Selenium and Oxidant Injury in Patients with Cystic Fibrosis
Malnutrition in cystic fibrosis (CF) has been associated with poor dietary intake, maldigestion and malabsorption of food, and increased nutrient requirements secondary to chronic: infection1. Recent studies have suggested that nutritional status influenced the progression of disease and nutritional supplementation was frequently included in the comprehensive management of this desease. But, children with exocrine pancreatic insufficiency, as observed in CF, might have secondary deficiency of the essential micronutrients specially Selenium (Se) deficiency2,3.
KeywordsCystic Fibrosis Cystic Fibrosis Patient Sodium Selenite Exocrine Pancreatic Insufficiency Butyl Hydroperoxide
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- 1.Park R.W., Granr R.J.: Gastrointestinal manifestations of cystic fibrosis: A review. Gastroentero1pgy 81:1149–1161.(1981)Google Scholar
- 2.Dworkin B., Newman L.J., Berezin S., Rosenthal W.S., Schwarz S.H., Weiss L. Low blood selenium levels in patients with cystic -fibrosis compared to controls and healthy adults. J. P. E. N. 11:38–41 (1987).Google Scholar
- 3.Vancaillie Bertrand M., De Bieville F., Neisens H., Kerrebijn K., Fernandes J. and Degenhart H. Trace metals in cystic -fibrosis. Acta Pediatr. Scand. 71:203–207 (1982).Google Scholar
- 4.W.A.Gunzler, H.Kremers, and L. Flohe. An improved coupled test procedure for glutathione peroxidase in blood. Z. Klin. Chem. Klin. Bigchem. 12:444– 448 (1974).Google Scholar
- 11.J.D.Llyd-Sti11, H.E.Ganther.Selenium and glutathione peroxidase levels in cystic fibrosis. Pediatrìc5 65:1010–12 (1980).Google Scholar
- 12.P.Foucaud, P.Therond, M.Marchand, F.Brion, J.F.Demelier, J.Navarro. Selenium et Vitamine E au cours de la muc¤viscidose. Arch.Fr.Pediatr. 45:383–386. ( 1988) .Google Scholar