Antioxidant Properties of Vitamin E and Membrane Permeability in Human Fibroblast Cultures

  • Marc Conti
  • Martine Couturier
  • Frédérique Lemonnier
  • Alain Lemonnier
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 264)


α-tocopherol, the most active form of vitamin E (Vit. E) is considered as one of the chief cell components which maintains the structural and functional membrane integrity. It acts as a free radical scavenger preven ting the peroxidation of membrane fatty acids. The role of Vit. E in cell permeability is widely studied using artificial membranes, but only a few investigations were devoted to this effect in cell cultures 1,2.


Minimal Essential Medium Fibroblast Culture Membrane Fatty Acid Artificial Membrane Intracellular Cholesterol 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Marc Conti
    • 1
  • Martine Couturier
    • 1
  • Frédérique Lemonnier
    • 1
  • Alain Lemonnier
    • 1
  1. 1.Unité de Recherches d’Hépatologie Pédiatrique INSERM U 56Hôpital de BicêtreLe Kremlin-BicêtreFrance

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