Antioxidant Properties of Vitamin E and Membrane Permeability in Human Fibroblast Cultures
α-tocopherol, the most active form of vitamin E (Vit. E) is considered as one of the chief cell components which maintains the structural and functional membrane integrity. It acts as a free radical scavenger preven ting the peroxidation of membrane fatty acids. The role of Vit. E in cell permeability is widely studied using artificial membranes, but only a few investigations were devoted to this effect in cell cultures 1,2.
KeywordsMinimal Essential Medium Fibroblast Culture Membrane Fatty Acid Artificial Membrane Intracellular Cholesterol
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- 6.J.M. Mc Cord, and I. Fridovich, Superoxide dismutase, an enzymic function for erythrocuprein (hemocuprein), J. Biol. Chem. 244:6049 (1969).Google Scholar
- 10.T. Fujii, A. Tamura, H. Fujii, I. Miwa, J. Okuda, Effect of exoge nous lipids incorporated into the membrane of human erythrocytes, on its glucose-transport activity. Biochem. Intern. 12:873 (1986).Google Scholar