Extracellular-Superoxide Dismutase, Distribution in the Body and Therapeutic Applications
Extracellular-superoxide dismutase (EC 22.214.171.124, EC-SOD) is a secretory, tetrameric, Cu and Zn-containing glycoprotein with a subunit molecular weight of about 30 kDa.1,2 EC-SOD is the major SOD isoenzyme in extracellular fluids.3,4 Although it is the least predominant SOD isoenzyme in the tissues, 90 to 99 % of the EC-SOD in the bogy of mammals is located to the extravascular space of tissues.5,6
KeywordsHeparan Sulfate Subunit Molecular Weight Creatine Kinase Release Potassium Superoxide Oxygen Radical Research
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