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Endocrine Abnormalities in Patients with Endstage Renal Failure

  • F. Kokot
  • A. Wiecek
  • W. Grzeszczak
  • J. Klepacka
  • M. Klin
  • M. Lao
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 260)

Abstract

Renal failure is associated with major endocrine abnormalities. These abnormalities seem to be caused not only by the reduced excretory and biodegradatory functions of the diseased kidneys, but also as consequence of the adaptive mechanism to renal failure and the accumulation of uraemic toxins. Additionally, nutritional factors and medical treatment may influence the type and magnitude of endocrine abnormalities noted in renal failure patients 1 , 2 .

Keywords

Atrial Natriuretic Peptide Opioid Peptide Endstage Renal Failure Recombinant Human Erythropoietin Endocrine Abnormality 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Osten, B., Kokot F. and Klinkmann, H.: Endokrinologische Störungen bei chronischer Niereninsuffizienz und bei Dauerdialysebehandlung. Teil 1, Renale Hormone-Hypophyse. Dtsch. Gesundh.-Wesen 37:2113 (1982).Google Scholar
  2. 2.
    Osten, B., Kokot, F. and Klinkmann, H.: Endokrinologische Störungen bei chronischer Niereninsuffizienz bei Dauerdialysebehandlung. Teil 2, Schilddrüse-Nebenschilddrüse-Gastrin-Pancreas-Nebennier e-Gonaden. Dtsch. Gesundh.-Wesen 37:2196 (1982).Google Scholar
  3. 3.
    Bostwick, D.G., Null, W.E., Holmes, D., Weber, E., Barchas, J.D. and Bensch, K.G.: Expression of opioid peptides in tumors. N. Engl. J. Med. 317:1439 (1987).PubMedCrossRefGoogle Scholar
  4. 4.
    Kriger, D.T.: Endorphins and enkephalins, in “Yearbook Medical Publishers”, Chicago (1982).Google Scholar
  5. 5.
    Pfeiffer, A. and Herz, A.: Endocrine actions of opioids. Horm. Metabol. Res. 16:386 (1984).CrossRefGoogle Scholar
  6. 6.
    Clement-Jones, V. and Besser, G.M.: Clinical perspectives in opioid peptides. Br. Med. Bul. 39:95 (1984).Google Scholar
  7. 7.
    Grzeszczak, W., Kokot, F. and Dulawa, J.: Effects of naloxone administration on endocrine abnormalities in chronic renal failure. Am. J. Nephrol. 7:93 (1987).PubMedCrossRefGoogle Scholar
  8. 8.
    Grzeszczak, W., Kokot, F. and Dulawa, J.: Einfluss von Naloxone auf die Parathormon- und Calcitoninsekretion bei Kranken mit akuter und chronischer Niereninsuffizienz. Z. Klin. Med. 41:435 (1986).Google Scholar
  9. 9.
    Grzeszczak, W., Kokot, F. and Dulawa, J.: Wplyw naloksonu na sekrecje insuliny i glukagonu u chorych na ostra niewydolnosc nerek (Influence of naloxone on insulin and glucagon secretion in acute renal failure) . Pol. Tyq. Lek. 41:331 (1986).Google Scholar
  10. 10.
    Massry, S.G.: Current status of the role of parathyroid hormone in uremic toxicity. Contrib. Nephrol. 49:1 (1985).PubMedGoogle Scholar
  11. 11.
    Kokot, F., Stupnicki, R.: “Metody radioimmunologiczne i radiokompetycyjne stosowane w klinice” (Radioimmunoassay and radiocompetitive methods used in clinical practice). PZWL, Warszawa (1985).Google Scholar
  12. 12.
    Kühn, K., Talartschik, H., Koch, K.M., Eisenhauer, T., Nonnast-Daniel, B., Scheler, Brunkhorst, R. and Reiner, E.: Plasma atrial natriuretic peptide after partial correction of renal anaemia by recombinant human erythropoietin. Nephrol. Dial. Transplant. 3: 497 (1988) (Abstract).Google Scholar
  13. 13.
    Schaefer, R.M., Kokot, F. and Heidland, A.: Normalization of prolactin levels and improved sexual function in dialysis patients on erythropoietin. Nephrol. Dial. Transplant. 3:501 (1988) (Abstract).Google Scholar
  14. 14.
    Bommer, J., Del Pozo, E., Ritz, E. and Bommer, G.: Improved sexual function in male haemodialysis patients on bromocriptine. Lancet 2:496 (1979).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • F. Kokot
    • 1
  • A. Wiecek
    • 1
  • W. Grzeszczak
    • 1
  • J. Klepacka
    • 2
  • M. Klin
    • 1
  • M. Lao
    • 2
  1. 1.Department of Nephrology Silesian School of MedicineKatowicePoland
  2. 2.Institute of TransplantationMedical Academy of WarsawPoland

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