Effects of Long-Term Treatment with Human Recombinant Erythropoietin in Patients on CAPD

  • Hjalmar B. Steinhauer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 260)


Anemia is a common feature in patients with chronic renal failure on regular dialysis treatment. The inappropriate low level of serum erythropoietin is known to be the major cause of anemia in these patients1. The development of recombinant human erythropoietin (rHuEPO) offers for the first time the possibility of an effective and continuous correction of renal anemia2 , 3 . In recent publications several authors described an increase of hematocrit in patients undergoing regular hemodialysis during treatment with rHuEPO2–7. In the initial trials rHuEPO treatment was associated with various adverse effects such as hypertension, convulsions, fistula clotting, and increased serum creatinine, urea, and potassium 2–4.


Continuous Ambulatory Peritoneal Dialysis Recombinant Human Erythropoietin Whole Blood Renal Anemia Continuous Ambulatory Peritoneal Dialysis Patient 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Hjalmar B. Steinhauer
    • 1
  1. 1.Department of Internal Medicine, Division of NephrologyUniversity of FreiburgGermany

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