Abstract
Since the first description of continuous arteriovenous hemofiltration as a method of emergency fluid removal (Kramer et al. 1977), this measure has gained wide acceptance predominantly as a supportive treatment of acute renal failure in critically ill patients. It has been shown that the machinefree hemofiltration allows liberal parenteral nutrition without the risk of fluid overload. In addition it has some capacity to remove uremic toxins. The method can be applied without sophisticated apparative equipment and without trained dialysis personal being familiar with the problems of extracorporal circulation.
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Bennett W.M., Aronoff G.R., Morrison G., Golper T.A., Pulliam J., Wolfson M., Singer I., 1983, Drug prescribing in renal failure: Dosing guidelines for adults, Am. J. Kidney. Dis., 3: 155.
Bodenham A., Shelly M.P., Park G.R., 1988, The altered pharmacokinetics and pharmacodynamics of drugs commonly used in critically ill patients, Clin. Pharmacokin., 14: 347.
Bozkurt F., Hörl W.H., 1987, Bedeutung der kontinuierlichen arteriovenösen Hämofiltration (CAVH) und arteriovenösen Hämodiafiltration (AV-HDF) in der Intensivtherapie, Intensivmed., 24: 248.
Drusano G.L., Standiford H.C., 1985, Pharmacokinetic profile of Imipenem/Cilastatin in normal volunteers, Am. J. Med., 78: 47.
Gibson T.P., Demetriades J.L., Bland J.A., 1985, Imipenem/Cilastatin: Pharmacokinetic profile in renal insufficiency, Am. J. Med., 78 (suppl. 6 a): 54.
Golper T.A., Pulliam J., Bennett W.M., 1985, Removal of therapeutic drugs by continuous arteriovenous hemofiltration, Arch. Int. Med., 145: 1651.
Golper T.A., Saad A.M.A., Morris CD., 1986, Gentamycin and Phenytoin sieving through hollow fiber polysulfone hemofilters, Kidney Int., 30: 937.
Hilt H., Keller F., 1987, Elimination von Pharmaka durch Hämofiltration, Anästh. Intensivther. Notfallmed., 22: 278. Kates R.E., Leier C.V., 1987, Dobutamine pharmacokinetics in severe heart failure, Clin. Pharmacol. Ther., 24: 537.
Kates R.E., Leier C.V., 1987, Dobutamine pharmacokinetics in severe heart failure, Clin. Pharmacol. Ther., 24: 537.
Keller E., Fecht H., Böhler J., Schollmeyer P., 1989, Single dose kinetics of Imipenem Cilastatin during continuous arteriovenous hemofiltration in intensive care patients, Nephr. Dial. and Transplant., (submitted).
Kramer P., Wigger W., Rieger J., Mattheai D., Scheler F., 1977, Arteriovenous hemofiltration : a new and simple method for treatment of overhydrated patients resistant to diuretics, Klin. Wochenschr., 55: 1121.
Lau A.H., Kronfol N.O., John E., 1987, Increased vancomycin elimination with continuous hemofiltration, Trans. Am. Soc. Artif. Intern. Organs., 33: 772.
Norrby S.R., Rogers J.D., Ferber F., Jones K.H., Zachei A.G., Weidner L.L., Demetriades J.L., Gravellese D.A., Hsieh Y.K., 1984, Disposition of radiolabeled Imipenem and Cilastatin in normal human volunteers, Antimicrob. Agents. Chemother., 26: 707.
Reeves D.S., Chapman S.T., Davies A.J., Ferber V.F., Rogers J.D., 1983, Human pharmacokinetics of N-Formimidoyl thienamycin alone and in combination with a dehydropeptidase inhibitor (MK 791 ) and probenecid. In: Spitzy KH, Karrer K eds., Proceedings of the thirteens International congress of Chemotherapy. Vienna, Austria, Vol 3, part 95: 30.
Stevens P.E., Riley B., Davies S.P., Gower P.E., Brown E.A., Kox W., 1988, Continuous arteriovenous hemodialysis in critically ill patients, Lancet 2: 150.
Vanholder R., Landschoot N.V., De Smed R., Schoots A., Ringoir S., 1988, Drug protein binding in chronic renal failure: Evaluation of nine drugs, Kidney Int., 33: 996.
Zarowitz B.J., Anandan J.V., Dumler F., Jayashankar J., Levin N., 1986, Continuous arteriovenous hemofiltration of aminoglycoside antibiotics in critically ill patients. J. Clin. Pharmacol., 26: 686.
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© 1989 Plenum Press, New York
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Keller, E. (1989). Drug Therapy During Continuous Arteriovenous Hemofiltration. In: Hörl, W.H., Schollmeyer, P.J. (eds) New Perspectives in Hemodialysis, Peritoneal Dialysis, Arteriovenous Hemofiltration, and Plasmapheresis. Advances in Experimental Medicine and Biology, vol 260. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5718-6_12
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DOI: https://doi.org/10.1007/978-1-4684-5718-6_12
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