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Strategies for the Development of a Rotavirus Vaccine Against Infantile Diarrhea with an Update on Clinical Trials of Rotavirus Vaccines

  • Conference paper
The Immune Response to Viral Infections

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 257))

Abstract

It is an honor and privilege to participate in this Symposium on “The Immune Response to Viral Infections” in this historic, celebrated city of countless renowned splendors where artistic and intellectual giants such as Leonardo da Vinci, Michelangelo, Dante, Machiavelli, Giotto, Botticelli, Galileo, Cellini, The Medici and the navigator Amerigo Vespucci exerted such profound influence, for it was here that Florentine scholars, painters, architects and craftsmen began the Renaissance. Although this pinnacle of human expression was unleashed with such intensity beginning some 500 years ago, thus laying the foundation for striking artistic, cultural and intellectual achievements, it is ironic that this energy did not successfully pollinate concurrently the domain of medicine since progress in discovering the etiologic agents of various scourges of humankind and elucidation of means to eliminate them were not forthcoming for centuries. Indeed, the mortality rate in the 15th century was quite high as documented in the Florentine dowry records of under one year to 19 year old females, with the highest rate occurring, by far, in the less than 5 year-old age group (Morrison et al., 1977).

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Authors and Affiliations

  1. Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892, USA

    Albert Z. Kapikian, Jorge Flores, Karen Midthun, Yasutaka Hoshino, Kim Y. Green, Mario Gorziglia, Kazuo Nishikawa & Robert M. Chanock

  2. Flow Laboratories, Inc., McLean, Virginia, 21202, USA

    Louis Potash

  3. Central University of Venezuela, Caracas, Venezuela

    Irene Perez-Schael

Authors
  1. Albert Z. Kapikian
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  4. Yasutaka Hoshino
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Editor information

Editors and Affiliations

  1. National Institute for Medical Research, London, UK

    B. A. Askonas

  2. National Institutes of Health, Bethesda, Maryland, USA

    B. Moss

  3. World Health Organization, Geneva, Switzerland

    G. Torrigiani

  4. Fondazione Internazionale Menarini, Florence, Italy

    S. Gorini

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© 1989 Plenum Press, New York

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Kapikian, A.Z. et al. (1989). Strategies for the Development of a Rotavirus Vaccine Against Infantile Diarrhea with an Update on Clinical Trials of Rotavirus Vaccines. In: Askonas, B.A., Moss, B., Torrigiani, G., Gorini, S. (eds) The Immune Response to Viral Infections. Advances in Experimental Medicine and Biology, vol 257. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5712-4_9

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  • DOI: https://doi.org/10.1007/978-1-4684-5712-4_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5714-8

  • Online ISBN: 978-1-4684-5712-4

  • eBook Packages: Springer Book Archive

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