Hepatitis Delta Virus and Autoantibodies to Epithelial Cells
It is well established that chronic liver disease (CLD) due to hepatitis delta virus (HDV) is associated with a variety of autoantibodies (Crivelli et al., 1983; Zauli et al., 1984; Zauli et ai., 1986). The type of autoantibody which appears to segregate more closely with such condition is certainly the basal cell layer antibody (BCLA). BCLA decorates in immunofluorescence the basal cells of squamous epithelia, such as rat fore stomach which is currently used to detect the antibody in human sera (Lenkei et al., 1983).
KeywordsChronic Liver Disease Squamous Epithelium Double Immunofluorescence Thymic Epithelial Cell Hepatitis Delta Virus
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- Crivelli, O., Lavarini, C, Chiaberge, E., Amoroso, A., Farci, P., Negro, F., and Rizzetto, M., 1983, Microsomal autoantibodies in chronic infection with the HBsAg associated delta agent. Cli. exp. Immunol., 54:468.Google Scholar