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Hepatitis Delta Virus and Autoantibodies to Epithelial Cells

  • Fabio Miserocchi
  • Daniela Zauli
  • Emilio Pisi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 257)

Abstract

It is well established that chronic liver disease (CLD) due to hepatitis delta virus (HDV) is associated with a variety of autoantibodies (Crivelli et al., 1983; Zauli et al., 1984; Zauli et ai., 1986). The type of autoantibody which appears to segregate more closely with such condition is certainly the basal cell layer antibody (BCLA). BCLA decorates in immunofluorescence the basal cells of squamous epithelia, such as rat fore stomach which is currently used to detect the antibody in human sera (Lenkei et al., 1983).

Keywords

Chronic Liver Disease Squamous Epithelium Double Immunofluorescence Thymic Epithelial Cell Hepatitis Delta Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Crivelli, O., Lavarini, C, Chiaberge, E., Amoroso, A., Farci, P., Negro, F., and Rizzetto, M., 1983, Microsomal autoantibodies in chronic infection with the HBsAg associated delta agent. Cli. exp. Immunol., 54:468.Google Scholar
  2. Lenkei, R. , Biberfeld, G., Magnius, L.O., Fagraeus, A., and Biberfeld, P., 1985, Autoantibodies to the basal cells of squamous epithelium react with thymic epithelial cells. Clin. Immunol. Immunopathol., 34:11.PubMedCrossRefGoogle Scholar
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  4. Zauli, D., Fusconi, M., Crespi, C, Bianchi, F.B., Craxiì, A., and Pisi, E., 1984, Close association between basal cell layer antibodies and hepatitis B virus-associated chronic delta infection. Hepatology, 4:1103.PubMedCrossRefGoogle Scholar
  5. Zauli, D., Crespi, C, Bianchi, F.B., Craxì, A., and Pisi, E., 1986, Auto immunity in chronic liver disease caused by hepatitis delta virus. J. Clin. Pathol., 39:897.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Fabio Miserocchi
    • 1
  • Daniela Zauli
    • 1
  • Emilio Pisi
    • 1
  1. 1.Istituto di Clinica Medica IIUniversity of BolognaBolognaItaly

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