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Delta Virus Hepatitis

  • Mario Rizzetto
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 257)

Abstract

The Hepatitis Delta Virus (HVD) occupies a unique niche in humai virology. At variance with conventional animal viruses, it cannot replicate autonomously but requires the presence of the Hepatitis B Virus (HBV) to initiate infection. It behaves like a defective interfering agent, in that it ihibits the synthesis of the competent HBV helper once its infection is established. This cooperation is reflected in the HD virion, a 36 nm spherical particle formed by an envelope of HBV-derived surface antigen (HBsAg), which encloses the genome and a specific delta antigen (HD-Ag) (1).

Keywords

Fulminant Hepatitis Hepatitis Delta Virus Helper Virus Woodchuck Hepatitis Virus Defective Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Mario Rizzetto
    • 1
  1. 1.Divisione di GastroenterologiaMolinetteTorinoItaly

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