The epithelium of the gastrointestinal (GI) tract undergoes constant rapid renewal. This process is an important mechanism of mucosal protection throughout the GI tract because it maintains the functional integrity of the epithelium and is also necessary for the repair of mucosal injury. Thus, it is reasonable to expect that certain conditions and agents that predispose to peptic ulcer disease or mucosal injury may do so in part by affecting epithelial renewal in the upper GI tract.
KeywordsMucosal Injury Chronic Gastritis Gastric Inhibitory Polypeptide Epithelial Proliferation Proliferative Zone
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