Molecular Characterization of Fibroblast Growth Factor and Possible Role in Early and Late Embryonic Development

  • Denis Gospodarowicz


In recent years growth factors have been shown to influence the in vitro proliferation and differentiation of endocrine cells (1). It has been postulated that they could play an important in vivo role in local control mechanisms involving either autocrine or paracrine regulation of endocrine cell proliferation and/or differentiation (1). Through their ability to modulate each other’s activity, they are well suited to control the complex morphogenetic events taking place in various organs during embryonic development or in specialized endocrine organs such as ovaries or testis during the adult phase (2,3).


Fibroblast Growth Factor Granulosa Cell Sertoli Cell Corpus Luteum Basic Fibroblast Growth Factor 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Denis Gospodarowicz
    • 1
  1. 1.Cancer Research Institute M-1282University of California Medical CenterSan FranciscoUSA

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