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Differential Responses in the Component Cells of Graafian Follicles Perifused with Large and Small Doses of LH

  • D. Olson
  • C. J. Hubbard
  • B. A. Oxberry

Abstract

Oocytes in developing graafian follicles remain arrested at the prophase stage of meiosis I until the follicles are exposed to the preovulatory LH surge. The LH surge triggers the resumption of meiosis and the oocytes progress to the metaphase stage of meiosis II through the process of oocyte maturation.

Keywords

Granulosa Cell cAMP Level Oocyte Maturation Cumulus Cell Pregnant Mare Serum Gonadotropin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Makris A, Ryan K. Cyclic AMP and cyclic GMP accumulation in hamster preovulatory follicles stimulated with LH and FSH. Acta Endocrinol (Copenh) 1978; 87:158–63.Google Scholar
  2. 2.
    Hubbard C. Cyclic AMP changes in the component cells of Graafian follicles: possible influences on maturation in the follicle-enclosed oocytes of hamsters. Dev Biol 1986; 118:343–51.PubMedCrossRefGoogle Scholar
  3. 3.
    Oxberry B, Greenwald G. An autoradiographic study of the binding of [125]I-labeled follicle-stimulating hormone, human chorionic gonadotropin and prolactin to the hamster ovary throughout the estrous cycle. Biol Reprod 1982; 27:505–16.PubMedCrossRefGoogle Scholar
  4. 4.
    Tarkowski A. An air-drying method for chromosome preparations from mouse eggs. Cytogenet 1966; 1:391.Google Scholar
  5. 5.
    Midgley A, Zeleznik A, Rajanjemi H, Richards J, Reichert L. Gonadotropin receptor activity and granulosa luteal cell differentiation. In: Moudgal NR, ed. Gonadotropins and gonadal function. New York: Academic Press, 1974:416–29.Google Scholar
  6. 6.
    Carson R, Salamonsen L, Findlay J. Permeability of rat ovarian follicles to LH during development and luteinization. J Reprod Fert 1986; 76:663–76.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • D. Olson
    • 1
    • 2
  • C. J. Hubbard
    • 1
    • 2
  • B. A. Oxberry
    • 1
    • 2
  1. 1.Department of Biological SciencesNorthern Illinois UniversityDeKalbUSA
  2. 2.Department of Anatomy, School of MedicineTemple UniversityPhiladelphiaUSA

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