Mechanisms by Which Vasoactive Intestinal Peptide Regulate Baboon Granulosa Cell Steroidogenesis

  • Susan L. Silavin


Vasoactive intestinal peptide (VIP) has been shown to enhance steroid production in vivo in rabbits (1) and humans (2) and in vitro in prepubertal rat ovaries (3), isolated rat granulosa cells (4), as well as cultured baboon granulosa cells (5). In addition, Gozes and Tsafriri (6) have found VIP-encoding mRNA in rat ovaries, suggesting a local ovarian synthesis of VIP.


Granulosa Cell Vasoactive Intestinal Peptide Vasoactive Intestinal Polypeptide Steroid Production Progesterone Production 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Susan L. Silavin
    • 1
  1. 1.Department of Obstetrics and Gynecology, Health Sciences CenterUniversity of OklahomaOklahoma CityUSA

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