Abstract
In order for gonadotropins to stimulate granulosa cells, they must first bind to their respective receptors which are located on the surface membrane (1). This binding initiates a cascade of yet undefined events which ultimately leads to a signal being sent to the nucleus which, in turn, induces mitosis and steroidogenesis. These two physiological processes could be the result of differential activation of “mitogenic” and “steroidogenic” gene systems.
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© 1989 Plenum Press, New York
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Peluso, J.J., Pappalardo, A. (1989). PMSG Induction of C-Fos and C-Myc Proteins Within Granulosa Cells of Immature Rat Ovaries. In: Hirshfield, A.N. (eds) Growth Factors and the Ovary. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5688-2_28
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DOI: https://doi.org/10.1007/978-1-4684-5688-2_28
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