Initial Characterization of a Luteal Growth Factor for Ovarian Mesothelial Cells

  • Santo V. Nicosia
  • Beatriz O. Saunders


The ovarian surface epithelium is a modified mesothelial tissue which undergoes species-dependent morphogenetic events throughout life (1,2). The mechanisms regulating such events are poorly understood in spite of the relevance of this tissue in reproduction and cancer (3,4). We have postulated that ovarian mesothelial cells may be influenced by underlying growth signals based on the observation of highly polarized DNA synthesis and morphogenesis in the postovulatory rabbit ovary (5). In the present study, we report on the isolation, biological activity and initial characterization of a recently discovered intraluteal growth factor for rabbit ovarian mesothelial cells (6).


Corpus Luteum Growth Effect Ovarian Surface Epithelium Ovarian Surface Initial Characterization 


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Santo V. Nicosia
    • 1
  • Beatriz O. Saunders
    • 1
  1. 1.Department of Pathology, College of MedicineUniversity of South FloridaTampaUSA

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