Transforming Growth Factor Production and Action in the Ovarian Follicle: Theca Cell-Granulosa Cell Interactions

  • Michael K. Skinner


Cell-cell interactions have an important role in the physiology of an individual cell and a whole organ. Interactions between cells result in the maintenance or alteration of several parameters, including growth, function and differentiation. It is unlikely that any individual interaction could maintain and regulate all cellular processes. Therefore, a number of different types of cell-cell interactions are required. The types of specific cellular interactions possible have previously been categorized into environmental, nutritional and regulatory cell-cell interactions (1). The current manuscript will review the interactions between different cell types in the ovarian follicle which regulate cell growth.


Granulosa Cell Ovarian Follicle Primordial Follicle Theca Cell Granulosa Cell Proliferation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Michael K. Skinner
    • 1
  1. 1.Department of Pharmacology, School of MedicineVanderbilt UniversityNashvilleUSA

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