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The Role of Brain Protein Phosphatases 1 and 2A in the Regulation of Microtubule Assembly

  • Hideyuki Yamamoto
  • Yoshiki Saitoh
  • Kohji Fukunaga
  • Eishichi Miyamoto
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 255)

Abstract

Protein phosphatase C was purified from bovine brain and was considered to consist of 10 and 90 %, respectively, of the catalytic subunits of protein phosphatases 1 and 2A on the basis of the effects of ATP and inhibitor-2. We investigated the dephosphorylation of microtubule proteins and the autophosphorylated Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) by protein phosphatase C.

Keywords

Protein Phosphatase Catalytic Subunit Bovine Brain Dependent Protein Kinase Microtubule Assembly 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Hideyuki Yamamoto
    • 1
  • Yoshiki Saitoh
    • 1
  • Kohji Fukunaga
    • 1
  • Eishichi Miyamoto
    • 1
  1. 1.Department of PharmacologyKumamoto University Medical SchoolKumamotoJapan

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