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Regulation of Embryonic Smooth Muscle Myosin by Myosin Light Chain Kinase and by Protein Kinase C

  • Chapter
Calcium Protein Signaling

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 255))

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Abstract

The presence of developmentally regulated myosin isoforms in muscle tissues is well established (1–9). Cardiac myosin has been studied extensively, and three different isoforms have been identified (4,5). These myosin isoforms differ with respect to (a) their mobilities on nondenaturing Polyacrylamide gels (3), (b) subunit composition (3,4), and (c) actomyosin ATPase activities (4). Moreover, specific cardiac myosin isoforms are expressed following volume overload of the heart (2) and change depending upon thyroid hormone levels (5). Similarly, fiberspecific myosin isoforms are expressed in skeletal muscle, and the myosin isoform correlates with both the type of innervation and the sequence of electrical stimulation (6).

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Author information

Authors and Affiliations

  1. Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL, 60612, USA

    Primal de Lanerolle

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  1. Primal de Lanerolle
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Editor information

Editors and Affiliations

  1. Nagoya University, Nagoya, Japan

    H. Hidaka

  2. Swiss Federal Institute of Technology, Zurich, Switzerland

    E. Carafoli

  3. Baylor College of Medicine, Houston, Texas, USA

    A. R. Means

  4. Mie University School of Medicine, Mie, Japan

    T. Tanaka

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© 1989 Plenum Press, New York

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de Lanerolle, P. (1989). Regulation of Embryonic Smooth Muscle Myosin by Myosin Light Chain Kinase and by Protein Kinase C. In: Hidaka, H., Carafoli, E., Means, A.R., Tanaka, T. (eds) Calcium Protein Signaling. Advances in Experimental Medicine and Biology, vol 255. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5679-0_34

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  • DOI: https://doi.org/10.1007/978-1-4684-5679-0_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5681-3

  • Online ISBN: 978-1-4684-5679-0

  • eBook Packages: Springer Book Archive

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