Sarcolemmal (Ca2+ + Mg2+)-ATPase of Vascular Smooth Muscle
The existence of a plasmalemmal ATP-dependent Ca2+-pump that extrudes Ca2+ out of the smooth muscle cells against its electrochemical gradient is well established and has been studied by measuring the ATP-dependent accumulation of Ca by microsomal fractions of smooth muscles.
KeywordsATPase Activity Vascular Smooth Muscle Malachite Green Microsome Fraction Dependent Protein Kinase
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- Jones, L. R. and Besch, H. R. Jr., 1984, Isolation of canine cardiac sarcolemmal vesicles, Methods Pharmacol., 5:1.Google Scholar
- Popescu, L. M., Panoiu, C., Hinescu, M. and Nutu, O., The mechanism of cGMP-induced relaxation in vascular smooth muscle, Eur. J. Pharmacol., 107:393Google Scholar
- Suematu, E., Hirata, M. and Kuriyama, H., 1984, Effects of cAMP-and cGMP-dependent protein kinase, and calmodulin on Ca2+ uptake by highly purified sarcolemmal vesicles of vascular smooth muscle, Biochim. Biophys. Acta, 773:83.Google Scholar