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High-Performance Liquid Chromatographic Method for Simultaneous Screening of the Deficiencies of APRT and HPRT

  • Toshihiro Nishina
  • Ryozo Sakuma
  • Tsukasa Kojima
  • Motoshi Kiyamura
  • Naoyuki Kamatani
  • Kusuki Nishioka
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 253A)

Abstract

Adenine phosphoribosyltransferase (APRT, EC 2.4.2.7) and hypoxanthine phosphoribosyltransferase (HPRT, EC 2.4.2. 8) are purine salvage enzymes and catalyze the formation of adenosine monophosphate (AMP) and inosine monophosphate (IMP) from adenine, hypoxanthine and phosphoribosyl-pyrophosphate (PRPP).

Keywords

Adenylate Kinase Alkaline Region Hypoxanthine Phosphoribosyltransferase Inosine Monophosphate Adenine Phosphoribosyltransferase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Toshihiro Nishina
    • 1
  • Ryozo Sakuma
    • 1
  • Tsukasa Kojima
    • 1
  • Motoshi Kiyamura
    • 1
  • Naoyuki Kamatani
    • 2
  • Kusuki Nishioka
    • 2
  1. 1.Department of Clinical ChemistryToranomon HospitalTokyoJapan
  2. 2.Institute of RheumatologyTokyo Women’s Medical CollegeTokyoJapan

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