Purine and Pyrimidine Metabolism of Normal and Leukemic Lymphocytes
Abnormalities in purine and pyrimidine metabolism may be associated with cell-cycle phase, proliferation, immaturity or transformation. Therefore, detailed information concerning purine and pyrimidine pattern in malignant cells compared to normal cells is needed. Abnormal enzyme activities (1) as well as abnormal metabolite concentrations (2) have been described for leukemic cells.
KeywordsAdenosine Deaminase Pyrimidine Metabolism Pyrimidine Synthesis Adenosine Deaminase Activity Leukemic Lymphocyte
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