AMP Catabolism in Primary Rat Cardiomyocyte Cultures

  • Esther Zoref-Shani
  • Genia Kessler-Icekson
  • Oded Sperling
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 253A)


The mechanisms operating to maintain an optimal adenine nucleotide pool in tissues are interrelated with the metabolism of AMP, This compound is the parent adenine nucleotide molecule to be produced, either de novo or by salvage. At the same time AMP is also the substrate for adenine nucleotide degradation to diffusible nucleosides and bases, which can efflux from the tissue (1, 2, 3, 4).


Adenine Nucleotide Adenosine Deaminase Purine Nucleoside Purine Nucleoside Phosphorylase Adenylate Energy Charge 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Esther Zoref-Shani
    • 1
    • 2
  • Genia Kessler-Icekson
    • 1
    • 2
  • Oded Sperling
    • 1
    • 2
  1. 1.Department of Chemical PathologyTel-Aviv University Sackler School of MedicineTel-AvivIsrael
  2. 2.Rogoff-Wellcome Medical Research Institute and Department of Clinical BiochemistryBeilinson Medical CenterPetah-TikvaIsrael

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