Should Dietary Restrictions Always Be Prescribed in the Treatment of Gout?

  • Antonio A. González
  • Juan G. Puig
  • Felícitas A. Mateos
  • Manuel L. Jiménez
  • Esperanza Casas
  • Ma. C. Capitán
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 253A)


Primary gout has been related to obesity, gluttony and alcoholic beverages abuse (1, 2). The decreased incidence of gout during periods of poverty (First and Second World Wars) supports the theory that favours overindulgence as a precipitating cause of gout. Purine-restricted diets have been shown to diminish serum urate concentrations and urinary uric acid excretion by 0.6–2.0 mg/d1 and 200–400 mg/24 h, respectively (3–5). This fact has led most authorities to recommend a purine-restricted diet as a cornerstone in the treatment of gout. Furthermore, primary gout is frequently associated with other disturbances requiring dietary restrictions, namely: obesity (6–13), arterial hypertension (7, 11, 13–16), hyper-lipidaemia (9, 13, 17–20) and diabetes mellitus (21). However, long-term patient compliance with purine-restricted diets may be difficult, especially in patients with a chronic disease who enjoy purine-rich food and alcoholic beverages.


Uric Acid Serum Uric Acid Restricted Diet Serum Urate Serum Urate Level 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Antonio A. González
    • 1
  • Juan G. Puig
    • 1
  • Felícitas A. Mateos
    • 1
  • Manuel L. Jiménez
    • 1
  • Esperanza Casas
    • 1
  • Ma. C. Capitán
    • 1
  1. 1.Departments of Internal Medicine and Clinical Biochemistry “La Paz” HospitalUniversidad AutónomaMadridSpain

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