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A Role of Interleukin-1 (IL-1) in Crystal-Induced Arthritis

  • Kumiko Hashizume
  • Minoru Sasano
  • Makoto Goto
  • Nobuyuki Miyasaka
  • Kusuki Nishioka
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 253A)

Abstract

Monosodium urate (MSU) crystals play a crucial role in the pathogenesis of gouty arthritis. MSU have been shown to be phagocytosed by polymorphonucelar cells, chondrocytes and synovial cells resulting in the release of prostaglandins and proteolytic enzymes (1).

Keywords

Synovial Tissue Synovial Cell Peripheral Blood Monocyte Gouty Arthritis Monosodium Urate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Kumiko Hashizume
    • 1
  • Minoru Sasano
    • 1
  • Makoto Goto
    • 1
  • Nobuyuki Miyasaka
    • 1
  • Kusuki Nishioka
    • 1
  1. 1.Institute of RheumatologyTokyo Women’s Medical CollegeTokyoJapan

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