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Family Study of Hereditary Xanthinuria — Decreased Duodenal Xanthine Oxidase Activity and Increased Urinary Excretion of Xanthine and Hypoxanthine in Heterozgotes

  • Masanori Kawachi
  • Norio Kono
  • Ikuo Mineo
  • Naoko Hara
  • Seiichi Himeno
  • Yuya Yamada
  • Hiroaki Kiyokawa
  • Tomoyuki Yamasaki
  • Yan Lin Wang
  • Masamichi Kuwajima
  • Seiichiro Tarui
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 253A)

Abstract

Hereditary xanthinuria is caused by a defect of xanthine oxidase (EC. 1.2.3.2) and inherited with an autosomal recessive manner (Auscher et al., 1977; Wilson et al., 1974). It is characterized by decrease of urate and increase of xanthine and hypoxanthine in blood and urine (Holmes et al., 1983).

Keywords

Xanthine Oxidase Glycogen Storage Disease Duodenal Mucosa Serum Urate Glycogen Storage Disease Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Masanori Kawachi
    • 1
  • Norio Kono
    • 1
  • Ikuo Mineo
    • 1
  • Naoko Hara
    • 1
  • Seiichi Himeno
    • 1
  • Yuya Yamada
    • 1
  • Hiroaki Kiyokawa
    • 1
  • Tomoyuki Yamasaki
    • 1
  • Yan Lin Wang
    • 1
  • Masamichi Kuwajima
    • 1
  • Seiichiro Tarui
    • 1
  1. 1.The Second Department of Internal MedicineOsaka University Medical SchoolJapan

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