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Continuous Crosscurrent Extraction of Proteins in Process Scale

  • Helmut Hustedt
  • Karl-Heinz Kroner
  • Neophytos Papamichael

Abstract

Automated continuous cross-current extraction of intracellular microbial enzymes from disrupted cells has been studied using a two-stage plant capable of processing 20–30 kg biomass per hour. The results reveal the feasibility of this advanced method of downstream processing by aqueous two-phase extraction.

Keywords

Bottom Phase Penicillin Acylase Crosscurrent Extraction Aqueous Phase System Continuous Crosscurrent Extraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Helmut Hustedt
    • 1
  • Karl-Heinz Kroner
    • 1
  • Neophytos Papamichael
    • 1
  1. 1.GBF, Gesellschaft für Biotechnologische Forschung mbHBraunschweigGermany

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