Compositional Patterns in Vertebrate Genomes: Conservation and Change in Evolution

  • Giorgio Bernardi
  • Dominique Mouchiroud
  • Christian Gautier
  • Giacomo Bernardi
Part of the NATO ASI Series book series (NATO ASI, volume 169)


Three approaches have recently provided new insights into the organization and evolution of the nuclear genomes of vertebrates. They are all based on the compositional properties of genome segments ranging in size from about 1 Kb, for coding sequences, to 100 Kb, for DNA fragments. The rationale for these approaches is the fact that vertebrate genomes are mosaics of isochores, which are evolutionarily relevant structures (see the following paragraph).


Codon Position Vertebrate Genome Neutral Theory Compositional Pattern Compositional Shift 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Giorgio Bernardi
    • 1
  • Dominique Mouchiroud
    • 2
  • Christian Gautier
    • 2
  • Giacomo Bernardi
    • 1
  1. 1.Laboratoire de Génétique MoléculaireInstitut Jacques MonodParisFrance
  2. 2.Laboratoire de Biométrie, U.A. 243Université Claude Bernard Lyon ILyonFrance

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